BackgroundArtificial intelligence-powered conversational agents have immense potential to provide social companionship and support for older adults.However, the deployment of large language model (LLM)-based conversational robots for seniors faces various technical, user acceptance, and ethical challenges.ObjectivesThis systematic review aims to sy
Immune system of the inner ear as a novel therapeutic target for sensorineural hearing loss
Sensorineural hearing loss (SNHL) is a common clinical condition bedding resulting from dysfunction in one or more parts in the auditory pathway between the inner ear and auditory cortex.Despite the prevalence of SNHL, little is known about its etiopathology, although several mechanisms have been postulated including ischemia, viral infection or re
A New Series of Pyrrole-Based Chalcones: Synthesis and Evaluation of Antimicrobial Activity, Cytotoxicity, and Genotoxicity
In an effort to develop new potent antimicrobial and anticancer agents, new pyrrole-based chalcones were designed and synthesized via the base-catalyzed Claisen-Schmidt condensation of 2-acetyl-1-methylpyrrole with 5-(aryl)furfural derivatives.The compounds were evaluated for their in vitro antimicrobial effects on pathogenic bacteria and Candida s
Rotation Equivariant Convolutional Neural Networks for Hyperspectral Image Classification
Detection of surface material based on hyperspectral imaging (HSI) analysis is an important and challenging task in remote sensing.It is widely known that spectral-spatial data exploitation performs better than traditional spectral pixel-wise procedures.Nowadays, convolutional neural networks (CNNs) have shown to be a powerful Hair Accessories deep
Comparison of the human gastric microbiota in hypochlorhydric states arising as a result of Helicobacter pylori-induced atrophic gastritis, autoimmune atrophic gastritis and proton pump inhibitor use.
Several conditions associated with reduced gastric acid secretion confer an altered risk of developing a gastric malignancy.Helicobacter pylori-induced atrophic gastritis predisposes to gastric adenocarcinoma, autoimmune atrophic gastritis is a precursor of type I gastric neuroendocrine MANGANESE CHELATE 25MG tumours, whereas proton pump inhibitor