Barriers and enablers for the deployment of large language model-based conversational robots for older adults: A protocol for a systematic review of qualitative studies.

BackgroundArtificial intelligence-powered conversational agents have immense potential to provide social companionship and support for older adults.However, the deployment of large language model (LLM)-based conversational robots for seniors faces various technical, user acceptance, and ethical challenges.ObjectivesThis systematic review aims to sy

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A New Series of Pyrrole-Based Chalcones: Synthesis and Evaluation of Antimicrobial Activity, Cytotoxicity, and Genotoxicity

In an effort to develop new potent antimicrobial and anticancer agents, new pyrrole-based chalcones were designed and synthesized via the base-catalyzed Claisen-Schmidt condensation of 2-acetyl-1-methylpyrrole with 5-(aryl)furfural derivatives.The compounds were evaluated for their in vitro antimicrobial effects on pathogenic bacteria and Candida s

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Comparison of the human gastric microbiota in hypochlorhydric states arising as a result of Helicobacter pylori-induced atrophic gastritis, autoimmune atrophic gastritis and proton pump inhibitor use.

Several conditions associated with reduced gastric acid secretion confer an altered risk of developing a gastric malignancy.Helicobacter pylori-induced atrophic gastritis predisposes to gastric adenocarcinoma, autoimmune atrophic gastritis is a precursor of type I gastric neuroendocrine MANGANESE CHELATE 25MG tumours, whereas proton pump inhibitor

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